Functional dissection of the catalytic mechanism of mammalian RNA polymerase II
نویسندگان
چکیده
منابع مشابه
Molecular Dissection of Mammalian RNA Polymerase II Transcriptional Termination
Transcriptional termination of mammalian RNA polymerase II (Pol II) is an essential but little-understood step in protein-coding gene expression. Mechanistically, termination by all DNA-dependent RNA polymerases can be reduced to two steps, namely release of the RNA transcript and release of the DNA template. Using a simple nuclear fractionation procedure, we have monitored transcript and templ...
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15 صفحه اولRNA polymerase II transcription: structure and mechanism.
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ژورنال
عنوان ژورنال: Biochemistry and Cell Biology
سال: 2005
ISSN: 0829-8211,1208-6002
DOI: 10.1139/o05-061